Synonyms

Central and peripheral axonopathy of meadowsweet

Name of the disease in English

No name known

The disease in brief

This is a hereditary anomaly, manifested by the appearance of progressive paralysis of the pelvic limbs in calves from 2 weeks to 3 months of the Rouge des Prés breed. Its transmission is autosomal recessive and a screening test exists.

Clinic & diagnosis

The disease can be suspected when newborn or week-old calves of the Rouge des Prés breed show an uncoordinated gait that can lead to falling over or calves that walk in circles.

Typical sign of the disease

No description

Pictures

See below

Diagnostic formulas

No description

Differential diagnosis

-Hydranecephaly N205

-Ischemic-hypoxic encephalopathy N217

-Non-specific bacterial meningoencephalitis (or BHV5 virus or other) NV13.1

-Vitamin A deficiency NV21

-Hydranencephaly N205

Confirm a suspicion?

The anomaly can be confirmed by taking a blood sample on EDTA and sending it, with a descriptive sheet downloadable from ONAB.fr, to:

INRA – Jouy-en-Josas Research Center
UMR of Animal Genetics and Integrative Biology
Bovine Genetics and Genomics Team
Building 211, Domaine de Vilvert
78352 Jouy-en-Josas cedex

Prognosis and treatment

No treatment; the abnormality is always fatal.

Prevention

The screening test makes it possible to identify carriers of the gene among unaffected breeders.

References

Jerusalem L. (2013) How to deal with a congenital anomaly with nervous symptoms in a newborn ruminant - Faculty of Medicine of Créteil - 122 p.